In response to a question about non-diet lifestyle factors for managing migraine, from someone who has multiple publications in Nature-subsidiary journals pushing the idea of migraine as at least in part a metabolic disorder, following a lengthy Bit about how Blue Light Glasses are An Absolute Must to Reduce Oxidative Stress In The Eye:
Then we have toxins. Toxins in cleaning products, toxins in makeup -- for women -- toxins in perfume. Perfumes are unregulated; they have all sorts of crappy stuff in there, and these odorants go directly into the brain via the nose because the blood-brain barrier is broken in the nose; otherwise, we couldn't smell. So chemicals can go directly in there, which I believe is also why perfumes are such a potent migraine trigger -- and cigarette smoke.
Like. On the one hand they left it in, which means I am using it as a barometer for how much to trust anything else this person says, but. but. THE BLOOD-BRAIN BARRIER IS BROKEN IN THE NOSE.