I have now been on the new preventative for three and a half weeks, and three migraines, which means I have accumulated enough data to be tentatively hopeful.
Following my adventures in A&E, I picked up a prescription for 5mg prochlorperazine, to take up to three times per day as acute relief for migraine. At the very end of November, I started candesartan, an anti-hypertensive, at 2mg.
In that first week, I had one (ovulation-triggered) migraine. Not counting prodrome, it lasted about 26 hours -- compared to "definitely two days" as my typical duration for ovulation-related migraines. So: a bit on the short side, but nothing to be particularly impressed by.
I increased my dose to 4mg after a week; in the last seven days I've had another two migraines. This period has been slightly weird, but "two distinct migraines each lasting up to three days" has been the pattern for onset-of-menstruation migraine over the past few months.
... this time migraine #1 started on the evening of the 17th; I wasn't even quite sure that it was actually A Migraine as opposed to feeling slightly shitty, but I took a dose of prochlorperazine and was sufficiently compos mentis to keep coding that evening, and after a couple of hours took the sunglasses back off and, while delicate, was more-or-less back to normal. I was definitely fine again the following morning.
On the fifth day thereafter -- yesterday -- I achieved Yet Another Migraine. Late morning--early afternoon onset; curled up rather more miserably in bed in the dark, but it had fucked off again by lunchtime today, i.e. in less than 24 hours. Again, I took prochlorperazine as acute relief and that did help with the nausea and my general wretchedness.
The maximum dose of candesartan is 16mg.
I am not willing to go so far as to say it is Actually Working -- as I say, this is a kind of weird period anyway so "bodies, what even" is definitely a potential factor here -- but. I am... well, I am all of a sudden hopeful enough that I'm going to be really disappointed if I just revert to type next migraine, put it that way.
Following my adventures in A&E, I picked up a prescription for 5mg prochlorperazine, to take up to three times per day as acute relief for migraine. At the very end of November, I started candesartan, an anti-hypertensive, at 2mg.
In that first week, I had one (ovulation-triggered) migraine. Not counting prodrome, it lasted about 26 hours -- compared to "definitely two days" as my typical duration for ovulation-related migraines. So: a bit on the short side, but nothing to be particularly impressed by.
I increased my dose to 4mg after a week; in the last seven days I've had another two migraines. This period has been slightly weird, but "two distinct migraines each lasting up to three days" has been the pattern for onset-of-menstruation migraine over the past few months.
... this time migraine #1 started on the evening of the 17th; I wasn't even quite sure that it was actually A Migraine as opposed to feeling slightly shitty, but I took a dose of prochlorperazine and was sufficiently compos mentis to keep coding that evening, and after a couple of hours took the sunglasses back off and, while delicate, was more-or-less back to normal. I was definitely fine again the following morning.
On the fifth day thereafter -- yesterday -- I achieved Yet Another Migraine. Late morning--early afternoon onset; curled up rather more miserably in bed in the dark, but it had fucked off again by lunchtime today, i.e. in less than 24 hours. Again, I took prochlorperazine as acute relief and that did help with the nausea and my general wretchedness.
The maximum dose of candesartan is 16mg.
I am not willing to go so far as to say it is Actually Working -- as I say, this is a kind of weird period anyway so "bodies, what even" is definitely a potential factor here -- but. I am... well, I am all of a sudden hopeful enough that I'm going to be really disappointed if I just revert to type next migraine, put it that way.
(no subject)
Date: 2021-12-23 10:51 pm (UTC)(no subject)
Date: 2021-12-23 10:53 pm (UTC)Fingers crossed for actually helpful medication!
(no subject)
Date: 2021-12-23 11:43 pm (UTC)(no subject)
Date: 2021-12-24 12:54 am (UTC)(no subject)
Date: 2021-12-24 07:02 am (UTC)(no subject)
Date: 2021-12-24 11:50 am (UTC)I have thoughts on two things that have helped reduce the frequency and severity of my migraines somewhat, let me know if you're interested, I don't wanna be unsolicited-advicey.
(no subject)
Date: 2021-12-24 03:21 pm (UTC)(no subject)
Date: 2021-12-24 06:14 pm (UTC)(no subject)
Date: 2021-12-24 07:31 pm (UTC)