culinary tangents

[kaberett]

One of the things I did this evening while finalising a Sous Chef[1] order was go through East double-checking whether there was anything shelf-stable she calls for that (i) I don't yet own, and (ii) was actually available from this particular source.

The answer to that particular question was no, but in the process -- part of the point of this exercise being to work out whether "cook everything from that book that I haven't yet" might be an entertaining Project for the year[2] -- I wound up diverting to looking up whether pomelo has the same drug interactions as grapefruit. (There's a salad.)

The answer to that question is "yes, probably, and also so do lime and Seville oranges", at least according to Bailey et al. (2013), entitled (...) Grapefruit–medication interactions: Forbidden fruit or avoidable consequences?

WAIT WHAT, I said, WHAT THE FUCK. WHAT???

... and proceeded to experience the Emotional Rollercoaster of reading on to discover that the one reported adverse event was nephrotoxicity, relating to the use of drugs that prevent rejection of organ transplants, following

Marmalade, 1.5 kg eaten during preceding 1 wk

... and the subsequent clarification that not only did this event take place in the context of consuming one and a half kilograms of marmalade, it was, specifically, grapefruit marmalade.

... for some reason I am no longer feeling alarmed about my weekly consumption of, at most, five teaspoons of marmalade.

---

New toy from previous Sous Chef order: ridiculous cast-iron spice grinder. I am enjoying it a great deal, and also have discovered that it works much better or at least with fewer blisters if you, er, do not fill it entirely to the brim...

---

[1] If this looks like your idea of a good time, have a referral link for You Both Get £10 Off!

[2] Broadly yes; there are three or four recipes that are incompatible with Alexes, mostly for reasons of caffeine, and another couple with Integral Mayonnaise about which I am Extremely Dubious. But other than those...

Comments

[rugessnome]

That's ...a lot of marmalade. (according to the cited paper it was homemade by one of the patient's patients and ostensibly orange marmalade but "more than half" grapefruit).

(...I forget whether it was the tacrolimus that was part of that incident or its close relative pimecrolimus but I was given a topical form of one of them for my eczema two decades and change ago. However it sounds like the topical form shouldn't have interaction with grapefruit.)

[ewt]

It came up recently in conversation that an online friend's late ex-father-in-law (yes, really!) refused to give up his homemade Seville orange marmalade when taking some drug or other that interacts with it and so the arrangement he eventually came to with his doctor was that he was essentially prescribed the marmalade, the same (fairly generous I think) amount every morning, and they calibrated his meds from there. I think this is a very sensible approach.

[rydra_wong]

Okay, that's delightful (and very sensible!).

[katzenfabrik]

If it was my gran's homemade marmalade, I really do think I could get through a kilo and a half in a week. I'd have to work at it, though! It wouldn't be accidental.

This post also prompted me to run my irregular check on whether grapefruit interacts with my antidepressant, which seems to give a different answer each time. This time it's a yes. :(

(Hi, by the way! I have not been on DW for ages, but I am spending a bit more time here lately. Very happy to hear that things went so well with your surgery. <3)

[kaberett]

I have my own homemade marmalade! I'm still not eating that much of it even if I do try XD

[kaberett]

(Also hi hello it is delightful to see you <3)

[azurelunatic]

214-ish grams or 7.5 ounces of marmalade every day. Yes, I'll take a scant half-pound of half-grapefruit marmalade on toast, every day...

[cesy]

Wait, lime does bad things with medication as well? How much lime?

[cesy]

Looks like it's only when you get to a whole fruit or 200ml of juice, at least for the grapefruit, so a dash of lime cordial is probably fine, and sweet tangerines etc are fine.

[kaberett]

As far as I can tell "vastly more than anyone is ever going to eat in one go" - I have decided I'm not going to worry about it!

[lokifan]

... for some reason I am no longer feeling alarmed about my weekly consumption of, at most, five teaspoons of marmalade.

LMAOOOOO.

[davidgillon]

Marmalade, 1.5 kg eaten during preceding 1 wk

*Boggle*

Glad to hear the grapefruit gives the oranges an alibi! Not for the marmalade - I'm not a fan - but for the oranges themselves. I don't eat many as a rule, but did work my way through a bag of tangerines over Christmas.

[kaberett]

Tangerines are fine anyway! It's the specific bitter-component that's the problem AIUI :-)

[rydra_wong]

I have a Skeppshult cast-iron frying pan and there is something deeply satisfying about it.

[kaberett]

Oooooh!

[rydra_wong]

This is the first time I have successfully figured out how to cook with/care for cast iron (there was a failed attempt in my twenties).

[ursamajor]

I was nodding along with the grapefruit-medication interaction bit and then blammed right into the 1.5 KILOS OF MARMALADE bit and now I can't stop laughing my ass off, even knowing I put 2 full tablespoons of blackberry jam onto my toast this morning because otherwise there would've been an annoyingly tiny amount of jam left to put back in the fridge.

On the other hand, if I or H or some combination of the both of us could eat 1.5 kilos of marmalade per week, maybe we wouldn't have accumulated such a large collection of jams and jellies and fruit preserves (I think we have like 27 jars of jam the last I looked).

[pseudomonas]

1.5kg is probably a normal intake if you're Paddington.

[azurelunatic]

One of the reasons for that warning is: Florida, USA.

Because Florida Man sometimes has a grapefruit tree in his backyard, and eats two grapefruits for breakfast every day.