thank you so so SO so much, this suddenly makes sense of my Weird Lung Shit and atypical responses to medication (in particular we tried me on the thing with the massive dose of ventolin and there was absolutely no difference in pulmonary function, I just had the massive fuckin' shakes); will read through this all in detail but it hadn't occurred to me that might be an interaction and NOW I HAVE WAYS TO HUNT SHIT DOWN.